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Computational Biologist

Research

Computational Biologists design and apply mathematical models, algorithms, and statistical methods to answer fundamental biological questions — protein folding mechanisms, regulatory network dynamics, evolutionary selection pressures, population-scale variant architecture, and single-cell lineage tracing. In India, the role sits at a small number of well-funded nodes: academic labs at NCBS Bangalore, IISc, IIIT-Hyderabad (CCNSB), CSIR-IGIB Delhi, and CSIR-CCMB Hyderabad; industry positions at Strand Life Sciences (Reliance), MedGenome, Biocon's biosimilars discovery arm, and agri-genomics startups. The GenomeIndia project (10,000 Indian whole-genomes) and the DBT-funded NABI Mohali have created new demand for population-genetics and demographic inference expertise specifically. The defining skill boundary: a computational biologist builds the method (a new variant-effect predictor, a phylogenetic inference engine, a protein structure scoring function); a bioinformatics scientist runs an existing pipeline against new data.